Bio-inspired hydroxyapatite dual core-shell structure for bone substitutes - Université Polytechnique des Hauts-de-France Accéder directement au contenu
Article Dans Une Revue Journal of the European Ceramic Society Année : 2017

Bio-inspired hydroxyapatite dual core-shell structure for bone substitutes

Résumé

A variety of processing methods has been developed and optimized to generate porous bio-ceramic structures close to that of the natural bone. Two different ceramic processing techniques were combined in order to generate a bio-inspired structure similar, in terms of composition and architecture, to that of the bone. Hydroxyapatite was manufactured through aqueous precipitation and complied with international standard ISO 13779's requirements. The impregnation of a polymeric scaffold by slurry enabled the manufacturing of a porous network reminiscent of spongy bone (the core) whereas ice templating generated the outer structures (the shell) very similar to compact bone. The core-shell structure was mechanically characterized thanks to longitudinal compression and the Brazilian test (traction test). According to porosity levels, the compression and Brazilian tests yielded values ranging from 30 down to 1 MPa and 4.6 down to 0.5 MPa, respectively. Porosity levels ranged from 36 up to 54%.

Domaines

Matériaux
Fichier non déposé

Dates et versions

hal-03079738 , version 1 (17-12-2020)

Identifiants

Citer

Shaan Chamary, D. Hautcoeur, Jean-Christophe Hornez, Anne Leriche, Francis Cambier. Bio-inspired hydroxyapatite dual core-shell structure for bone substitutes. Journal of the European Ceramic Society, 2017, 37 (16), pp.5321-5327. ⟨10.1016/j.jeurceramsoc.2017.05.043⟩. ⟨hal-03079738⟩
42 Consultations
0 Téléchargements

Altmetric

Partager

Gmail Facebook X LinkedIn More