The paper proposes an original framework to design cooperative eco-driving (economic driving) rail control system called CEDRICS. A generic method to design cooperative support system is applied to build CEDRICS by taking into account real human behaviors to recalculate on-line advices for train eco-driving. An experimental study on a tramway simulator was performed to compare different configurations of CEDRICS considering or not human behavior constraints with same interfaces. Results show relevant benefits in using CEDRICS face to complex environmental contexts involving interactions with cars and/or pedestrians.