Aircraft cabin is considered as a hostile environment for low mobility passengers, especially around seat interaction. Improving air travel experience, and more specifically sit-tostand (STS) and seat exit could be done through digital human modeling, and there is a need for a first description of STS ergonomic in order to properly design such a model. An experimental setup was built that reproduces actual aircraft cabin geometry, associated with motion capture devices, to describe STS and exit strategy of low mobility passengers. Results showed that subjects relied on several sequential strategies composed of hand positions and trunk bending. Those results will help to define model parameters for future large scale studies based on simulation, to improve accessibility of aircraft seats