Objectives Chronic pain syndromes are frequently associated with balance disorders [1]. For example, studies showed a linear relationship between pain and stability [1] in no-specific low back pain [2]. The reexamination of the links between nerves and pain [3] modifies the traditional perception of these chronic pain syndromes without organic cause and these neural dysfunctions. The aim of this communication is to propose a new, original and innovative clinical approach to the management of chronic pain syndrome by the use of postural investigation and neurosensory stimulation. Methods The neurosensory Posturotherapy [3] uses a simple methodology to understand neural physiology through a palpatory sensory evaluation and then to perform manual neurostimulation. These stimulations include the neural saturation of the dysfunctional nerve associated with a sideration of muscles innervated by the nerve being treated. This approach can be completed by plantar neurostimulations inducing postural remediation. Results Firstly, the dysfunction of a nerve is associated with hypertonia of the muscles which it innervates. Secondly, the nervi nervorum compose the intrinsic innervations of nerve sheath. They are polymodal receptors located at the periphery of the nerve sheath. They encode the mechanical information exerted on the nerve. The response of the mechanoreceptors increases with the intensity of the stimulation up to a plateau and then decreases from a threshold value. Thirdly, pressure and vibration, exerted with intensity higher than the threshold value, induces a saturation of the response of the mechanoreceptor. Lastly, the saturation points used by the treatment are most often found at the points of cutaneous emergence of the nerve. Conclusion The neurosensory Posturotherapy is a simple method of diagnosis and treatment of neural dysfunction involved in neuropathic pain and balance disorders. It represents a new therapeutic contribution in the management of subjects with specific chronic pain syndrome.